An efficient and new protocol for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) 4(a-m) has been developed by using Zn(OAc)2 as a catalyst. This is one of the useful new catalyst that can be easily separated and are not contaminated by products. This method offers several advantages including high yields, short reaction times, simple work up procedure and easy isolation.