Indicators help to determine the equivalent point of an acid base titration. Today synthetic indicators are extensively used in the acid-base titrations. But due to environmental impact, availability and cost, the requirement for natural compounds as an acid-base indicator has increase. These natural indicators are found to be a very useful, economical, simple, available and eco-friendly. The present investigation highlights the usefulness of Basella alba fruit extract as natural acid-base indicator in titrations. This natural indicator is easy to extract as well as easily available. Promising results were obtained when it was compared against Phenolphthalein, a popularly used synthetic acid-base indicator. Titrations at different conditions showed sharp color change at the equivalence point. The equivalence points obtained by the fruit extract and standard indicator coincide with each other.