This study aimed to examine the polyphenol and flavonoid contents of different solvent extracts of Bassia muricata with antioxidant activity by measuring the radical 2,2-diphenyl-1-picylhydrazyl scavenging activity and antibacterial activity by using disc diffusion method. The total phenol content amongst the extracts were significantly higher in butanol extract (199.80 μg GAE mg-1) and decreased in the following order: butanol extract > ethanol extract > ethyl acetate extract. Antioxidant activity was also highest for butanol extract (p<0.05). Antioxidant activity was generally found to increase with total phenol content (TFC) and total flavonoid content (TFC). Bassia muricata extracts have shown significantly antibacterial activity against various gram-positive and gram-negative bacteria. The highest antibacterial activity has shown with butanol extract.