The aim of our research was to establish structure-antiradical activity relationships of the synthetic analogues of naturally occurring antioxidants - avenanthramides. We studied the influence of the position of carboxylic group in aniline moiety and substituents in the cinnamic acid moiety. It was found out that the position of carboxylic group did not have any significant impact on the antiradical activity of compounds in DPPH test; opposite situation was observed in case of feruloyl anilines in GO assay.