A novel series of Carboxamide derivative of N-(3-fluoro-4-morpholinophenyl)-3-methyl-5-(methylthio)-1Hpyrazole- 4-carboxamide have been synthesized by using different aromatic acid chloride in very good yield. The structures of the synthesized compounds have been characterized by using IR, 1H NMR and Mass spectroscopy. All the prepared new NCEs were screened for anti microbial activity and anti fungal activity.