The Transition Schiff base complexes derived from Benzoinoxime and transition metal halides has been prepared and characterized. Several physical tools in particular, elemental analysis, infrared and 1H NMR spectroscopy were used to investigate the chemical structure of the prepared compounds. The elemental analysis data shows 1:2 [M: L] ratio. The infrared spectral data of the complex display the complexation behaviour of the Schiff base towards metal ions. The free Schiff base and the complexes have been tested for their antibacterial and antifungal activities against several bacteria and fungi, the obtained result showed enhancement in activity on coordination of metals with ligands.