The synthesis of new divalent Schiff base on the Lanthanide (III) complexes like La (III), Ce(III), Nd(III), Sm(III), Gd(III), Tb(III) and Dy(III) were derived by the condensation of salicylaldehyde with 4-methoxyaniline in alcoholic medium with forming 2-(E)-(4-methoxyphenylimino) methyl phenol (MPMP) The structures of the Schiff base ligands and Lanthanide (III) complexes have been proposed by the analytical and spectral data by FTIR, 1HNMR, Molar conductance, XRD and Magnetic studies. The XRD studies indicate that orthorhombic crystal system for Ce(III), Nd(III), Tb(III), Dy(III) and Gd(III) complexes and other were tetrahedral crystal system for La(III) and Sm(III) complexes. The diameters inhibition zone were measured after 24 hrs of incubation [Gd(MPMP)2((H2O)2NO3] were found to be effective against Staphylococcus aureus in 500 ppm solution. The MPMP ligands metal complexes have been tested for their antibacterial activity against Staphylococcus aureus, Bacillus substilis species and antifungal activity Aspergillus Niger, Fusarium Oxysporum species at the same concentration 250 ppm and 500 ppm.