Schiff base synthesis of pyrazolone derivatives containing Indole moiety bearing-4-oxazetiding ring were synthesized by the condensation of 2-(3-(3chloro -1-(4-substitued phenyl )-4-oxozetiding -2-yl(1H-Indole –yl Aceto hydrazone with ethyl 2-(2-(4-substitued phenyl hydrazone)(-4,-4,-4 tri frouro-3-oxo butanoate) this reaction was subjected in schiff base reaction .The structure of these newly synthesized compounds were characterized by 1H NMR,13CNMR ,Mass ,IR, and elemental analysis