In an effect to develop antimicrobial activity, four copolyesters were synthesised from 1, 3-bis (4-hydroxy-3- methoxyphenyl) propenone (BHMPP) and 1- (3, 5-dihydroxyphenyl)-3-(4-methoxyphenyl) propenone (DHPMPP) by Phase transfer catalysed polycondensation with adipoyl, suberoyl, azeloyl and sebacoyl chlorides. These copolyesters were characterised by solubility data and viscosity measurements. The microstructure of the repeating unit was confirmed by IR, 1H and 13C NMR. These copolyesters displayed potential antimicrobial activity against fungal and bacterial strains.