Quinazolinone and their derivatives have been studi ed extensively for various biological activities such as anti-inflammatory, antimicrobial, antitumor , antioxidant and anti-HIV activity. Schiff bases have also been exploited extensively for antimicrob ial and antioxidant activities. In the present investigation various quinazolinone amines have bee n clubbed with five membered heterocyclic aldehydes to obtain the title compounds. All the sy nthesized compounds have been screened for their antibacterial activity against S.aureus, B.subtilis, E.coli and K.pneumonia and invitro antioxidant activity by 1,1-diphenyl-2,2-picryl hydrazyl free r adical (DPPH) method.