In this study, twelve new coordination compounds of nickel(II) and copper(II) carboxylates with urea and thiourea have been synthesized and screened for their fungicidal activities against some rotten wood fungi namely streptomyces xantholiticus, four strains of rhizopus oryxae and lactobacillus plantarum; two strains of lactobacillus fermentum, mucor racemosus and aspergillus niger The results showed that the complexes inhibited the growth of streptomyces xantholiticus, rhizopus oryxae, aspergillus niger lactobacillus plantarum, lactobacillus fermentum, and mucor racemosus and aspergillus niger.