In the present study O,N,O-donating ligand was prepared from the condensation of 2-aminobenzohydrazide and 5- bromo-2-hydroxybenzaldehyde to give the Schiff base. The structure of the compounds has been confirmed by MASS, IR, NMR, 13C NMR, ESI MASS. The synthesized compounds were screened for their antibacterial and antifungal activities.