Synthesis and biological evaluation of some new Aryl acid N'-(1Hindazole- 3-carbonyl)-hydrazide derivatives

T. Ch; rasekhar; L. Vinay Kumar; A. Babul Reddy; P. Jagan Naik; G. Narayana Swamy

Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2012 Vol: 4 Issue: 5

Synthesis and biological evaluation of some new Aryl acid N'-(1Hindazole- 3-carbonyl)-hydrazide derivatives

Abstract

Amide coupling of 1H-Indazole-3-carboxylic acid hydrazide with substituted aryl acids affords thirteen novel Aryl acid N'-(1H-indazole-3-carbonyl)-hydrazide derivatives. The acid hydrazide was synthesized by the hydrazine reaction with 1-H-Indazole-3-carboxylic acid methyl ester which was obtained by esterification of indazole-3- carboxylic acid.