Tritium safety research on the tritium system of Test Blanket Module (TBM) was carried out. At first, according to safety conception of multiple containment systems, a possible layout of TBM tritium system was designed and analyzed. Secondly, according to safety analysis task and method of the tritium system, the research framework about tritium safety analysis was given. At last, in order to compare and assess safety grade about the tritium system among all kinds of nuclear facilities, calculation formula was given.