The medicinal plant Hemidesmus indicus R. Br. is extensively used in Ayurveda, the Indian school of traditional medicine. A large amount of work on different aspects of H. indicus has been carried out and reported over the years. The present review covers recent work on H. indicus which have not received adequate coverage in the reviews on this plant so far. The two aspects covered in this review are (i) the chemical constituents of H. indicus and (ii) anti-diabetic properties of H. indicus.