Downhole oil-water separation and reinjection technology can effectively solve the problem that the moisture of produced fluid is getting higher and higher, and as a key component of the injection-production system, injection-production string withstands packer's seating axial force, internal pressure, external pressure of oil and multi-load conditions, thereby resulting in the bending deformation of oil tube, and then causing the systems running eccentric wear, cards pumps and other phenomena. In this paper, the deformation of oil pipe between the injection-production system packers were mechanical simulation analyzed, and obtained the effective measures to reduce pipes bending deformation, to guarantee efficient and safe operation of the pipe, and then the injection-production system can run smoothly for a long time.