The study was conducted to estimate the queries received from different wards, pharmacies and from areas Outside RMI, and to assess quality of service provided by department of pharmacy Rehman medical institute Peshawar.The caller calls DPIC By dialling extension 3131 or direct phone 091-5838031, received by pharmacist documented in form prepared by department of pharmacy. At the end of each shift put the data from these forms into excel sheet. Data from excel sheet were retrospectively evaluated from August 2014 to August 2015 for various parameter like type of queries, caller, etc. A total of 5194 queries received over a period of 13 months. Highest in the month of june-2015 while that of lowest number of queries received in the month of Aug-2014.Caller with different specialty like consultants, Pharmacist, staff nurse and medical officer, of whom the percentage of medical officers were highest i.e.35.12%, while the lowest for technician i.e. 0.27%.The most frequent queries received by DPIC were for generic/brands20.54% while for alternate, contraindication, drug-drug interaction, adverse drug action, pregnancy/lactation and Indication, were7.91%, 0.48%, 0.94%, 1.23%, 1.58%, 5.74%, respectively. Answer to all queries was given by pharmacist within an average of 2 minutes per response. The drugs and poison information center at Rehman medical institute providing information regarding utilization of drugs and poison management asked by health care professional practicing at Rehman medical institute and outside, up- hilling toward better patient care.