Salacia species have been used in the traditional Ayurvedic system of medicine for the treatment diabetes. Salacia oblonga is one of the important medicinal plant of genus Salacia. This plant has numerous medicinal properties, viz. the root bark of Salacia oblonga is used for the treatment of rheumatism, gonorrhea and skin diseases. Different parts of this plant have various biological activities which are owing to the presence of important phytochemicals such as mangeferin, salcinol, kotanlol, with proven biological activities.