An experiment was conducted at Research Farm, NDUA&T, Kumarganj, Faizabad, during winter season 2007-08, to evaluate the performance of wheat under different moisture regime, water use and it’s efficiency. It was found that irrigation supplementation at 1.0 Irrigation water/Cumulative Pan Evaporation (IW/CPE) Ratio is significantly influence the growth and yield of wheat crop, while application of 125.0 % nitrogen significantly affected the growth and yield of crop, highest water use efficiency under the 4.0 cm irrigation at 1.0 IW/CPE ratio and 150 kg N ha-1.