Study the impact of benefit distribution on the equilibrium of R&D network cooperation, and find that if we introduce a mechanism of benefit transfer, the condition that make the n enterprises’ cooperation to become a Nash equilibrium will be loosen, which means that the mechanism of benefit transfer makes the cooperation become a Nash equilibrium in a wider range of circumstances. Know the mechanism of benefit transfer is conducive to formation of R&D network. Furthermore, study the feasible region and equilibrium solution of transfer coefficient, and get the equilibrium solution under the condition of individual optimum as well as the overall optimum.