Lantana camara locally named as Ghaneri in Marathi is found in the gardens as an ornamental plant and at the roadside of most of the cities. This plant has high medicinal value as recognized by Indian traditional folk. It is known antimicrobial, fungicidal, insecticidal and immune-depressant. Lantana oil is popular against skin infections generally used for the cure and care of leprosy patients. So, in the present study an attempt has been made to chemically reinvestigate the bio-active components in leaf extracts of Lantana camara extracted sequentially in NHexame, ethyl acetate, acetone, methanol and ethanol solvents. The chemical investigation of these extracts show the presence of terpenes, saponins in all extracts. Steroids are reported in all extracts except methanol. Falavonoids are present in n-hexane and ethyl acetate extracts. Carbohydrates are present in n-hexane, ethyl acetate and acetone extract. Glycosides are present in acetone and methanol extracts. Coumarins class of compounds is reported in ethyl acetate, acetone and methanol. Tannins, Phlobatannins, Alkaloids, Proteins, Emodins, Anthraquinones, Anthocyanins and Leucoanthocyanins classes of compounds are absent in all extracts. The probable number of compounds in each extracts determined using TLC.