In this present investigation, four different plants species including Ocimum sanctum, Zingiber officinale, Rosamarinus officinalis and Eucalypus globules were reviewed based on their considerable antioxidant, antitussive and expectorant properties. The average of total phenolic content was found to be 3.65 ±1.5mgGAE/gram; 17±12.3mgGAE/gram, 53.3±14.7mgGAE/gram and 102.75±57.4 mgGAE/gram while the average of total flavonoid content was found to be 0.205mgQE/gram; 4.18±1.9mgQE/gram; 22.74±7.7mgQE/gram and 35.03±1.03mgQE/gram of dried weight O. sanctum, Z. officinale, R. officinalis and E. globules, respectively. The compounds such as rosmarinic acid, ursolic acid, chlorogenic acid, zingiberene, camphene etc., were considered for their metabolites having an antitussive and antioxidant activities compounds of these plants. From these findings, we are in process to formulate new antitussive and expectorant formulation from these plant species either in their combination or as crude drugs or particular fractions obtained using adequate standardized methods