The pharmacological and biological properties and chemical constituents of plants from the plant Salacia Reticulata which is widely used in folk medicine. In the present study, the antiinflammatory activity of hexane and chloroform extracts of Salacia Reticulata were studied and the activity was compared with Diclofenac sodium. The anti-inflammatory activity was found out by Carragenan induced paw edema method by using standard Diclofenac sodium.In preliminary phyto chemical investigation the hexane and chloroform extracts showed the presence of carbohydrates, glycosides, Coumarins and phytosterols. In this acute inflammation model, both extracts and the standard drugs (diclofenac sodium 10mg/kg) produced significant inhibition of paw edema as compared to the control. The chloroform extract highly significant when compared to the hexane extract. The results were found to be highly significant (P< 0.01 ) in comparison to control.