Siddha system of medicine is one among the tradition system of India. This system having lot of medicines which are prepared from raw drugs of Herbal, Metal, Mineral and Animal origins. There are so many herbal, herbo-mineral formulations are available in Siddha system of medicine to treat Bronchial asthma effectively. One of the poly herbo mineral preparations ‘Kadukkai Vadagam’(KV) has been recognized as effective treatment for Swasakaasam (Bronchial asthma) mentioned in Siddha classical literature. But this drug formulation is not yet validated scientifically. In the Physiochemical analysis studies, KV has contains Total ash 15.12%, Water soluble ash 3.13%, Acid insoluble ash 0.68%, Water soluble extractive 44.00%, Alcohol soluble extractive 45.81%. Scanning Electron Microscope analysis shows that the particle size was 2 – 5 µ. ICP-OES (Inductively Coupled Plasma Optical Emission Spectroscopy) shows that the formulation is extremely safe as it contains heavy metals below detectable limits.