With the development of knowledge economic, the internet of things collaborative innovation is becoming an important way of science and technology innovation, knowledge sharing which as an effective operation support activity is not play a very good role. So the study of knowledge sharing incentive mechanism has the necessity. This paper which based on the principal-agent theory, constructing the basic incentive model and the incentive model considering monitoring signal of knowledge sharing in the internet of things collaborative innovation. Then we study the effect of incentive optimize model on increasing the degree of the science research institution’s effort, improving the rationality of knowledge sharing incentive mechanism, reducing the moral hazard and analyze the valid parameter condition of incentive mechanism