In the paper the significance of immune and etiotropic treatment of herpes-virus infections is presented, data have been generalized particularities of herpes simplex virus type 1 and type 2; the principal active ingredients, company-manufacturers and country-manufacturers of antiviral drugs have been analyzed; a comparative analysis of sales of antiviral drugs in packages and dollars for 2013 and 2014 in Ukraine has been conducted; the leading antiviral drugs on sales in packages and in dollars have been determined.