One of alkaloid compound was isolated from leaves Brugmansia candida. The compound was purified by chromatography column with silica gel as adsorbent. The purity of the isolated compound was tested by TLC, melting point. The structure of the compound was identified by means of spectroscopic include Ultraviolet Spectroscopy, Infrared Spectroscopy, and NMR. All data obtained indicates that the resulting compound is an isoquinolin alkaloid.