The fresh foliage of Indigofera astragalina collected from Gwiwa and Arkilla low cost areas of Wamakko local government area of Sokoto state, Nigeria were dried, powdered and subjected to nutritive and anti – nutritive investigation. The n-hexane, methanol, and water extracts prepared from the leaves were found to contain oxalates, phytate,tannins and cardiac glycosides, The proximate composition revealed the presence of moisture (51.00 ± 0.50 % fresh weight), ash (8.17 ± 0.58 % dry weight, DW), crude lipid (5.0 ± 0.5 % DW), crude fibre (2.67 ± 0.29 % DW), crude protein (8.23 ± 0.11 % DW) and carbohydrate (75.94 ± 0.64%). The Anti – nutritive compositions which are oxalate (2.26 ± 00mg/100g), phytate (12.26 ± 0.01mg/100g), cynogenic glycoside (0.24 ± 0.00mg/100g) and tannins (3.05 ± 0.02mg/100g). They also contained vitamin C (21.13mg/100g). The results of the analyses were compared with other green leaves consumed. These results releaved that the leaves of Indigofera astragalina contained medicinal agents.