The ethanolic extract of Zygophyllum album was extracted successively with chloroform, ethyl acetate and butanol. Using colorimetric methods, the higher content of phenols was recorded in crude extract and water fraction (5.118 ± 0.105 and 2.088 ± 0.012 mg GAE/g DW respectively), the higher content of flavonoids was found in crude extract and butanol fraction (2.393 ± 0.061 and 0.506 ± 0.013 mg QE/g DW respectively), and the higher content of tannins was recorded in crude extract and water fraction (197.875 ± 25.46 and 103.611 ± 49.235 mg RE/g DW respectively). All extracts showed very good activity of ferric reducing power, the higher power was in crude extract and butanol fraction (11.262 ± 0.38 and 30.177 ± 2.397 mM respectively) more effective than BHA and BHT. IC50 of inhibition of radical DPPH in chloroform fraction was 22.127±0.837μg/ml more effective than BHT.