Heavy metals exposure in animals can lead to profound effects in growth and development. It is necessary that heavy metal toxicity be well documented and adequate precaution should be taken in mother and fetus to decrease its detrimental effects. An experimental study was performed with viviparous animal Heterometrous fulvipes to access the cumulative effects on Bio chemical parameters on glycogen, glucose proteins, TNPS, and protein metabolism on chronic heavy metals exposure. Heavy metals disturb all most all functions in which proteins are involved and all most every protein in the body is a potential target. Heavy metals primarily cause biochemical lesions and affects in altering carbohydrate, protein and lipid metabolism. Chronic heavy metal exposure resulted in decrease in hepato pancreatic weight, hepato-somatic index and embryonic length with subsequent reduction and length and weight of the embryos.