Synthesis of nanomaterial with the desired quality and properties is one of the key issues in current nanotechnology. Today, the green synthesis of metallic nanoparticles has received increasing attention due to the development of eco-friendly technologies in materials science. Use of natural plant extracts in the preparation of nanoparticles by greener route provides advancement over chemical and physical method as it is cost effective, environment friendly. In the present work, copper nanoparticles have been synthesized with simple and green synthesis method by using lemon extract as a reducer and curcumin as a stabilizer under certain conditions. The obtained copper nanoparticles were characterized by UV-Vis, IR, XRD, SEM and TEM techniques. The experimental results showed that the particle size of copper nanoparticles was appreciable and the antimicrobial activities of synthesized nanoparticles were significantly higher.