Evaluation of prescribing indicators regularly helps to monitor the prescriptions to reduce indiscriminate use of drugs. As the data on prescribing patterns in orthopaedics is lacking, the present study was planned to analyze prescribing pattern and WHO Indicators in Orthopaedic inpatients at Victoria Hospital, Bangalore. Demographic, disease and drug data were collected from case records of patients. Data was analyzed by descriptive statistics. 100 inpatient prescriptions were analyzed, of which 73 were males while 27 were females. Duration of hospitalization was 8-10 days. Common orthopaedic diagnoses were fractures (44%), surgeries (26%) and joint dislocations (18%). Analgesics were most commonly prescribed drug class (31.25%), followed by gastroprotectives (23%) and antimicrobial agents (18.75%). Tramadol (40%) and diclofenac (26.67%) were commonly prescribed analgesics, while ceftriaxone (62.22%) and amikacin (28.89%) were common antimicrobials. 50% drugs were injectables. Average number of drugs per encounter was 4.8 (±1.2). Drugs prescribed by generic name were 60% and 85% of drugs were prescribed from essential drugs list. A new trend of prescribing tramadol was noted in the study. Polypharmacy and higher frequency of injections use was reported in the present study. Prescriptions of antibiotics, essential medicines and use of generic drugs were found to be satisfactory.