Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2015 Vol: 7 Issue: 9

Evaluation of antioxidant and antibacterial activities of endophytic fungi isolated from Bauhinia racemosa Lam and Phyllanthus amarusSchum and Thonn.

Abstract

The objective of this study is to screen the antioxidant and antibacterial activity of endophytic fungi isolated from surface sterilized leaves, stem and root of Bauhinia racemosa lam and phyllanthus amarus Shum and Thonn. 13 fungal species of endophytic fungi were isolated including Colletotrichum gleosporioides, Drechslera halodes, Nigrospora sphaerica, Phoma glomerata, from Bauhinia racemosa and Aspergillus nidulans, Chaetomiun spiralis, Colletotrichum circinans, Colletotrichum crassipes, Colletotrichum falcatum, Collectotrichum truncatum, Penicillium citrinum, Phoma chrysanthemicoli and Phyllosticta Sp from Phyllanthus amarus. The dominant fungi were evaluated for its antioxidant and antibacterial activity. Both the entophyte and the host extracts were extracted by water and methanol and tested for their total phenolic content and radical scavenging potentials. The fungal extracts were also assessed for antibacterial activity against bacterial strains: Bacillus subtilis and Escherichia coli. The results of the MIC study showed that the Chaetomium spiralis extracts exhibited higher activity against bacteria, Escherichia coli.

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