Although folk medicinal practitioners are common in rural areas, urban practitioners are a comparative rarity. It was thus of interest to document the ethnomedicinal practices of a folk medicinal practitioner of Dhaka city, which is the capital of Bangladesh and has a population nearing 20 million. The practitioner was observed to use a total of 30 plants distributed into 20 families in his formulations. The practitioner treated a number of difficult to cure diseases as well as common diseases. Cumulatively, the diseases that he treated included cancer, leukemia, diabetes, gastrointestinal disorders, various types of pain, poisoning of various organs of the body due to accumulation of toxins, heart disorders, vomiting, passing of blood with urine, hypertension, weakness, excessive excitement of nervous system, helminthiasis, rheumatism, urinary disorders, blood disorders, fever, respiratory tract disorders, insomnia, piles, kidney stones, skin disorders, heart disorders, menstrual disorders, cholera, malaria, cataract, hair loss, obesity, chicken pox, and weakness. The practitioner also used various plants or plant parts to maintain or improve functions of several major organs of the body. Taken together, the medicinal plants used for diseases treated by the practitioner can prove highly important for further scientific research towards curative as well as preventive purposes.