The chamomile (Matricari achemmomilla) belongs to Astraceae family that is native of Mediterranean moderate temperate and Asia, and has high pharmaceutical, nutritional, cosmetical and hygienic values. Because of active ingredients in the chamomile’s extract and essence such as terpenoids, ceraizin, coumarin, spiroters and flavonoids (including epigenin, luteolin, camazolin, bizabolol, sesquiterpene), lactones (such as matricarin), polysaccharides, capric and nownilic ethers, amplifrons, amino acids, fatty acids, phenolic acids, choline, and coumarin, matricin, bizabolol and its oxides and the cis & trans of ton-in-di-cycloether alpha-bizabolol and azolen has major effect in the treatment of various diseases of the nervous, digestive, respiratory, reproductive, muscular and skeletal systems. It is a valuable plant that can play an important role in the treatment of human diseases. In this paper, chamomillae plant is presented in various aspects such as ecology, species, health effects, ingredients, side effects, carcinogenic or mutagenic and disuse occasions.