Suzuki cross-coupling reaction of aryl halides with aryl boronic acid is one of the most important method for thesynthesis of biaryls, in recently the application of N,O-based ligands moiety, such as Schiff bases, guanidine, aryloximes, acetohydrazide, arylimines, has also consider as a highly active catalysts for Suzuki cross coupling reaction in aqueous media.[1-6]Nature of ligand is important in the Suzuki cross coupling reaction. Bulky and more electron-rich ligands are important in Suzuki cross-coupling reaction. Due to their higher donor ability and stability effects[7–10].Its present in pharmaceuticals, agrochemicals materials natural products, polymer, [11–18] .In recent Suzuki cross coupling reaction is carried out in aqueous phases including water and water/organic mixtures assolvents. comparatively to other solvent water is environmental friendly, easily available and easily for separation of organic products and catalyst recycling