The Objective of the study is to analyze the prescriptive pattern of antidiabetic drugs according to World Health Organisation(WHO)drug use indicators in diabetology outpatient clinic of a Tertiary care teaching hospital. A prospective cross-sectional study conducted was conducted for 4 months in Diabetology clinic, Sree Balaji Medical College Hospital. Adult diabetic patients of either sex ranging from 18-75 years who visit the Diabetology outpatient department was included in the study. Drug use indicators and defined daily dosage (DDD) were calculated in this study. A total of 508 prescriptions were collected and the average number of drugs per prescription was 1.25. 70.02% of generics and 96.62% of essential drugs have been prescribed. Metformin is most commonly prescribed among all antidiabetic drugs. The average consulting time were 8.78 min and dispensing time were 40.17 sec. The DDD/1000/day for Metformin was the highest(314.6)and Inj. Insulatard was the lowest (20.32).It was concluded that the incidence of polypharmacy is very low and that the generic and essential drug prescription is high and Metformin is most commonly prescribed among antidiabetic drugs.