Using Sunplus SCM SPCE061A as the control core, utilizing the method of combining hardware design with software design, a new type of intelligent voice electronic nose has been designed. The structure diagram of intelligent voice of electronic nose is introduced, the main unit circuits of the system and part of the software flow charts are given, and the selection of sensor is comprehensively expounded. Finally, the typical application of intelligent voice electronic nose in four kind’s food quality detection of fish, vegetables, fruit and meat is analyzed in detail. Repeated tests show that the correct rate of the intelligent voice electronic nose for food quality detection is more than 97%, and it can make the correct classification of food, the intelligent voice electronic nose has the advantages of simple structure, convenient use, high intelligent degree, higher accuracy rate, so it is worthy being spread and applied.