Orodispersible tablets of Valdecoxib, to disintegrate rapidly in the oral cavity upon contact with saliva by formation of easy to swallow suspension without the aid of water were prepared. Mass extrusion technique and sublimation methods were employed in designing of orodispersible formulations. In the present study, bitter taste of Valdecoxib was masked by using previously optimized ratio of Valdecoxib: Eudragit E -100. Orodispersible tablets were developed using the prepared taste masked granules and a mixture of excipients consisting of MCC and L-HPC by mass extrusion technique. Sublimation method also employed to formulate orodispersible tablets using camphor as subliming material and water-soluble materials like mannitol. Precompression parameters like angle of repose, % compressibility index results showed better flow properties. Hardness, friability, wetting time, water absorption ratio, in vitro disintegration were found to be well within the specification. The disintegration was achieved within 30 seconds from all the formulations prepared by both methods when observed in the saliva of healthy volunteers. The in vitro dissolution was almost 90% within 15 min for all formulations. Formulations of sublimation method were subjected for SEM study to evidence formation of porous cavities within the tablets, which were responsible for fast disintegration in the oral cavity. Selected formulations were subjected for stability studies for 30 days at different temperatures. Tablet properties were evaluated at different intervals. It is confirmed that Orodispersible tablets can be developed by mass extrusion technique and sublimation method.