Serious corrosion is often seen in high temperature oil well which affects its production heavily. On the basis of analyzing the corrosion reason and orthogonal array test, one corrosion inhibitor, HZG, is developed. HZG is aimed to deal with corrosion of high temperature oil well(>100℃)。The main constituents of HZG include imidazoline derivative, organic amine and fluor-carbon-imidazoline, which has good corrosion resistant capability, its average corrosion resistant percent is 90% and average corrosion resistant percent on field application is 82%. Field application shows that the HZG can solves most oil wells’s corrosion problems and has good corrosion resistant effect.