Oral cancers are one of the most communal cancers globally today. Oral cancer accounts for a expressively superior section of the entire cancer cases. They are typically unobserved by the general people when connected to systemic cancers such as the lung cancer, colon cancer etc. Survival rates of oral cancers are comparatively low in contrast to other major cancers, though incidence rates are as low as 3%. Though, they also might be exceptionally fatal if left untreated even at a very early stage of the lesion. Dental health care workers have a duty to perceive benign and it grants the whole dental team with significant duties, challenges and a real prospect to save life. Delay in diagnosis, metastases, and the existence of secondary tumors are the main reasons for the poor prognosis of oral cancers. The purpose of this paper is to offer a detailed review about the numerous advanced diagnostic aids in the diagnosis of oral cancer.