The comparative study of two main rivers Tista and Karola of Jalpaiguri take attention to some special aspects of this area. River Karola is passing through the main town but Tista is passing through outside the town. The measured values of some physico-chemical parameters show almost same ranges for the two rivers. It indicates that the sources of pollution are almost same type for two rivers. The parameters also prove that at the Karola - Tista meeting point contamination of water takes place. The agriculture of this area is directly and indirectly linked with the rivers. So pollution of water has a great impact on both the quality of growing crops and as well as aquatic life of this area. The continuing pollution from 2004 to 2014 of Karola was proved previously by same author. The present study also proves that river Tista follows the same trend from 2004 to 2014. pH, DO, EC, Alkalinity, BOD, Chloride, Fluoride, Phosphate, Hardness etc. were chosen as physico-chemical parameters for the comparison.