Polyurethane sorbent was developed by adding new chelating groups and changes the polarity of the matrix. The polyamine polyhalo polyurethane sorbent (PPPs) contains °1 amine, halogen, ether and urethane groups, which reveals its potential for extraction and recovery of iron(III) ions. The effects of different parameters including pH, shaking time, flow rate, temperature and initial concentration of iron were studied to optimize the presented procedure. Maximum sorption of Fe(III)ions on to PPPs was achieved in acidic medium (pH 1-2 and 5) at a period range 1-5 min. A perfect isotherm curve with zero intercepts (0.005), a good correlation (R2=0.986) has been obtained. The values of LOD, LOQ and RSD (n=6) for determination of Fe(III) ions are 3.0 ng L−1, 10.1 ng L−1, and 0.75%, respectively. The batch capacities of the PPClPs, PPBrPs and PPIPs were 0.133, 0.124 and 0.118mmolg–1, respectively. The accuracy of the procedure was verified by the analysis of iron drugs samples with recoveries were 100% which indicated that PPPs have a great potential to determine iron in real samples