Three Annona species, A. squamosa, A. cherimola and A. Abdel Razik were investigated for their volatile oils in leaves, qualitatively and quantitatively. GC/MS recorded that A. Cherimola contains 27.59% isocaryophylline. A. squamosa contains the highest percentage of copaene, α- pinene and β pinene in the following amounts, 17.06, 9.96 and 12.99 respectively. The oil showed potent antimicrobial activity against different pathogenic organisms. The investigation deals with the antioxidant content of the fixed and volatile oils. The fixed oil of the seeds contains higher amount of oleic and linoleic acids, where the the degree of the unsaturated fatty acids reaches over 70%.