The research about biosorption of Cu(II) by Nothopanax scutellarium leaves has been investigated through batch experiment. Based on the experiment optimum condition for adsorption Cu (II) ion was pH 7, biosorbent dosage at 0,1 g, initial concentration of metal ion solution 1200 mg/L and contact time 15 minutes. The biosorption data were fitted to Freundlich isotherm with R2 0.9848. Characterization of Nothopanax scutellarium was evaluated using Fourier Transform Infra Red (FT-IR) spectroscopy and active functional group estimated were O-H group, C-H group, N-H group and C-N group. The measurement of metal ion concentration conducted by Atomic Absorption Spectroscopy (AAS) and surface analysis before and after adsorption conducted using Scanning Electron Microscopy (SEM). This study showed that Nothopanax scutellarium leaves powder could be used as an efficient adsorbent to remove Cu (II) metal ions.