Application of the Pfitzinger reaction on indophenazino fused carbazole 4a and azacarbazoles 4(b-e) with isatin (5) yielded the corresponding indophenazino fused quinoline-4-carboxylic acid derivatives 6(a-e) in moderate to good yield. All quinoline-4-carboxylic acid derivatives were characterized on the basis of their microanalysis IR, 1HNMR and MS spectral data.