Click chemistry refers to a group of reactions that are fast, simple to use, easy to purify,versatile, regiospecific, and give high product yields. While there are a number of reactions that fulfill the criteria, the Huisgen 1, 3-dipolar cycloaddition of azides and terminal alkynes has emerged as the frontrunner. It has found applications in a wide variety of research areas, including materials sciences, polymer chemistry, and pharmaceutical sciences.