The present study investigatedthe antimicrobial potential of four medicinal plants viz., tulsi, amla, neem and henna against the pathogenic bacteria. The ethanolic extract of all medicinal plants exhibited maximum antimicrobial activity against all bacterial pathogens. The ethanolic extract of henna exhibited maximum antimicrobial potential against E. coli (19.6±0.27 mm) while that of amla exhibited maximum antimicrobial potential against E. coli (16.7±0.34 mm). The ethanolic extract of tulsi exhibited maximum antimicrobial potential against Klebsiella(13.3±0.47 mm) while the ethanolic extract of neem exhibited maximum antimicrobial potential against E. coli (15.4±0.20 mm).