Cashew nut shell liquid (CNSL) and its derivatives are widely used in polymer-based industries, synthesis of chemicals and intermediates including bactericides, insecticides and surface active agents. Commercially available CNSL mainly contains phenolic constituents such as anacardic acid, cardanol and cardol. Cardanol contains polymerizable side chain and phenolic group. Cardanol and its various derivatives have found numerous industrial applications. p -chloro aniline and p-nitro aniline have been diazotised and coupled with cardanol to produce diazotised-p-chloro aniline cardanol dye and diazotised-p-nitro aniline cardanol dye respectively. They have been characterized by, FT- IR and 1H-NMR spectroscopic techniques and their antibacterial activity has also been studied. Antimicrobial studies revealed that compound was showed significant activity against tested strains.