Over the current scenarios of the diseases, there are always new diseases being spread each day. The design of drugs to all those diseases is being the major role which complexes human minds for designing any drug. Therefore Drug discovery and development becomes an interdisciplinary, expensive and time-consuming process when executed on manual bases. Consequently the human minds are been replaced by the machines where computeraided applications have given rise as a major significant factor in the field of chemistry, which are specially designed to formulate drugs. There are a plenty of drug designing systems as of now designed under various categories with varying functionalities as well. An eye over these computer-aided drug design tools initiated this paper, which shows the brief overview on the various computer aided drug design tools in this field of chemical engineering industry.